BelleSculpt – Regenerative Bioactive Solution for Reducing Cellulite & Improving Tissue Firmness

BelleSculpt

peptide^®

Sterile solution

BelleSculpt peptide® is developed to address cellulite and improve overall tissue firmness. Its bioactive peptides promote smoother skin texture and restore elasticity.

Designed as a painless solution, it offers patients visible contour refinement and improved confidence

KEY BENEFITS

Reduces visible cellulite and skin irregularities.

Safe, painless, and clinically tested.

Improves tissue firmness and elasticity.

Enhances microcirculation in affected areas.

Supports extracellular matrix renewal for smoother skin.

SCIENTIFIC FOUNDATION

BelleSculpt peptide® acts by stimulating fibroblasts and supporting ECM remodeling in areas prone to cellulite.

By improving microcirculation and modulating inflammation, it helps restore firmer, smoother tissue.

HOW IT WORKS

Stimulates fibroblasts for ECM remodeling.

Enhances microcirculation to improve tissue health.

Supports smoother, firmer tissue in treated zones.

Modulates inflammation contributing to cellulite.

For professionals

BelleSculpt peptide® is suited for professionals offering advanced body-contouring solutions. Its sterile, preservative-free formulation ensures both safety and visible improvements in tissue quality.

DISCOVER

BelleSculpt

peptide^®

Ingredients

Main Actives

Sculptide™

Dipeptide-2, Pentapeptide-25, Acetyl Hexapeptide-39, Palmitoyl Tripeptide-1

Caffeine, TEA-Hydroiodide

Celldrain™

Asiaticoside, Ammonium Glycyrrhizate, Escin, Forskolin

Polyglucuronic Acid, Rutin

Sodium Hyaluronate, Complexia 55™

Indications

BelleSculpt is indicated for the professional treatment of cellulite and localized adipose tissue disorders, to be used exclusively under medical supervision, involving alterations of adipocytes, connective tissue, and microcirculation.

It is suitable for patients presenting with:

Fibrous (hard) cellulite: compact, painful or treatment-resistant cellulite with reduced tissue mobility, commonly observed in younger or athletic patients.
Soft (diffuse) cellulite: flaccid, non-painful cellulite associated with adipose tissue laxity, frequently related to aging, hormonal changes, or weight fluctuations.
Edematous cellulite: cellulite associated with fluid retention, impaired lymphatic drainage, tissue heaviness, or circulatory discomfort.
Localized adipose hyperplasia: circumscribed areas of excess adipose tissue accompanied by surface irregularities and uneven skin texture.
Visible skin surface irregularities, including dimpling and the characteristic “orange peel” appearance, present at rest or accentuated by compression.

The combined action of its active components supports multilevel tissue remodeling, acting on adipose metabolism, extracellular matrix quality, and microcirculatory function, with the objective of improving skin smoothness and tissue homogeneity.

Areas of application

Legs, hips, and buttocks.

Professional use only Treatment must be performed under the supervision of a licensed physician.

Medical INFO

Cellulite is a multifactorial disorder of the dermo–hypodermal unit, involving adipocyte dysfunction, connective tissue remodeling, microvascular impairment, interstitial fluid accumulation, and chronic low-grade inflammation. Its clinical expression varies according to the relative contribution of each component.

BelleSculpt has been developed to address these mechanisms simultaneously through a multilevel, biologically targeted approach, under medical supervision only.

Modulation of Adipocyte Metabolism
Lipolysis activation and fat mobilization: The combination of Caffeine, Forskolin, and TEA-Hydroiodide promotes intracellular cAMP signaling, leading to activation of protein kinase A (PKA) and downstream lipolytic enzymes, facilitating the breakdown of triglycerides into free fatty acids and glycerol. Reduction of adipocyte differentiation and lipid storage: Acetyl Hexapeptide-39 (Sculptide™) and Ammonium Glycyrrhizate (Celldrain™) contribute to regulating adipocyte biology and reducing lipid accumulation.
Mitochondrial Energy Regulation
Pentapeptide-25 (Sculptide™) supports mitochondrial uncoupling mechanisms associated with UCP pathways, promoting energy dissipation rather than storage.
Extracellular Matrix and Dermal Remodeling
Palmitoyl Tripeptide-1 (Sculptide™) and Asiaticoside (Celldrain™) support fibroblast activity and extracellular matrix synthesis, contributing to improved collagen structure. Sodium Hyaluronate, Polyglucuronic Acid, and Complexia 55™ enhance tissue hydration, viscoelasticity, and dermal turgor.
Microcirculation, Capillary Stability, and Edema Reduction
Escin (Celldrain™) supports venous tone and reduces capillary leakage, while Rutin strengthens capillary resistance. Dipeptide-2 (Sculptide™) contributes to microcirculatory regulation.
Anti-Inflammatory and Antioxidant Support
Ammonium Glycyrrhizate (Celldrain™) provides anti-inflammatory support, while Rutin contributes antioxidant protection.

By acting concurrently on adipocyte metabolism, connective tissue quality, microcirculation, and inflammation, BelleSculpt supports both short-term improvement in skin appearance and progressive tissue remodeling.

Professional use only. Treatment must be performed under the supervision of a licensed physician.

BelleSculpt peptide® is the regenerative bioactive solution for reducing cellulite and improving tissue firmness. Contact Persebelle to bring this innovation into your clinic.