Eyebelle – Regenerative Bioactive Solution for Eye Contour Rejuvenation
Eyebelle
Eyebelle peptide® is a targeted peptide-based solution specifically developed for the delicate eye contour. It helps reduce dark circles, under-eye puffiness, and fine lines, restoring a fresher, more lifted appearance.
This painless treatment supports a brighter, smoother, and visibly rejuvenated eye area, with excellent tolerance and natural-looking results.
KEY BENEFITS
Reduces appearance of dark circles under the eyes.
Safe, gentle, and developed for professional use.
Diminishes puffiness and swelling around the eyes.
Smooths fine lines and expression lines in the eye contour.
Improves skin firmness and elasticity in the eye contour.
SCIENTIFIC FOUNDATION
Eyebelle peptide® is powered by peptides that improve microcirculation and reduce pigmentation under the eyes.
By strengthening the dermal matrix and enhancing hydration, it restores brightness and firmness to the eye area.
HOW IT WORKS
Advance regulation of melanogenesis. Improves microcirculation to reduce dark circles.
Clearance of hemoglobin-derived pigments.
Inflamatory edema control.
Dermal matrix reinforcement of the lower eyelid.
Optimization of periorbital microcirculation.
For professionals
EyeBelle peptide® is ideal for professionals targeting eye contour rejuvenation. Its sterile, preservative-free formula ensures both safety and visible results in delicate areas.
Ingredients
Main Actives
Addwhite™: Tranexamic Acid, Tranexamoyl-Dipeptide-23, α-Arbutin and Niacinamide
Ophira™: Hesperidin, Chrysin, Glycyrrhizate and N-Hydroxysuccinimide
PDRN
Peptides: Oligopeptide-1, Tetrapeptide-7, Tripeptide-5 and Dipeptide-2
Hyaluronic Acid, in a specialized combination of molecular weights
Complexia 55™, a plasma-like nutrient-rich complex
Indications
Eyebelle peptide® can be use to treat the following:
– Eye shadow, dark circles caused by hyperpigmentation
– Eye edema below lower lid that gives appearance of puffiness
– To avoid the increase of the vasculature in the area, avoiding angiogenesis
– Reinforce the extra thin skin in the area
Treatment areas: skin around eyes below lower lid.
The application of Eybelle peptide® requires medical supervision.
Medical INFO
Clinical Positioning
Eyebelle Peptide™ is a multi-pathway professional formulation designed for the treatment of periorbital dark circles and puffiness of mixed etiology, where pigmentation, vascular factors, hemoglobin degradation, edema, and structural skin thinness coexist.
It is particularly suitable as a first-line treatment in patients presenting with complex or combined dark circle phenotypes.
Pathophysiological Targets
Melanic Hyperpigmentation
Inhibition of tyrosinase, TRP-1 and TRP-2
Downregulation of MITF-driven melanogenic signaling
Modulation of melanocortin (MC1R) pathways
Interference with melanosome transfer
Reduction of ROS-mediated melanogenic stimulation
Clinical relevance: Reduces brown or mixed dark circles and limits progression of pigmentation.
Vascular and Hemodynamic Dark Circles
Regulation of periorbital microvasculature
Reduction of capillary congestion
Stabilization of vascular dynamics
Clinical relevance: Improves bluish discoloration and vascular visibility.
Hemoglobin Degradation By-Products
Reduction of biliverdin, bilirubin and iron residues
Clinical relevance: Addresses persistent vascular dark circles resistant to classic depigmenting agents.
Periorbital Edema and Puffiness
Improved microcirculatory efficiency
Reduced fluid extravasation
Modulation of COX-2 and PGE₂ inflammatory pathways
Clinical relevance: Reduces infraorbital swelling and puffiness.
Structural Fragility of Periocular Skin
Peptide-mediated collagen and elastin support
Extracellular matrix reinforcement
Supportive hydration via hyaluronic acid
Clinical relevance: Improves skin density, resilience and reduces translucency.
Clinical Use and Integration
Compatible with microneedling, roller-assisted delivery, IPL-associated protocols, RF, laser and other medical-aesthetic procedures.
Formulation Quality
Sterile, preservative-free, pyrogen-free. Manufactured using aseptic filling techniques.
Eyebelle peptide® is the regenerative bioactive solution for a brighter and smoother eye contour. Contact Persebelle to bring innovation to your aesthetic practice.
