BelleVline – Regenerative Bioactive Solution for Jawline Definition & Submental Fat Reduction
BelleVline
BelleVline peptide® is a facial contouring solution designed to gently and precisely reshape lower facial contours, restoring harmony to the jawline and reducing double chin fullness.
Its formulation is specifically adapted to the sensitive tissues of the face, modulating adipose tissue metabolism without inducing inflammation or tissue stress.
This painless, non-aggressive approach delivers natural-looking contour refinement while fully respecting facial physiology.
KEY BENEFITS
Targets submental fat under the chin.
Safe, painless, and professional-grade.
Improves jawline definition and contour.
Supports skin firmness in the lower face.
Reduces puffiness and heaviness around jaw area.
SCIENTIFIC FOUNDATION
BelleVline peptide® works through peptides that enhance lipolysis and dermal support in the lower facial region.
By reinforcing ECM stability and modulating inflammatory pathways, it improves contour precision and reduces submental fullness..
HOW IT WORKS
Stimulates lipolysis in submental areas.
Strengthens extracellular matrix for firmness.
Enhances circulation to promote tissue remodeling.
Supports jawline definition with regenerative peptides.
For professionals
BelleVline peptide® is designed for aesthetic professionals seeking advanced solutions for facial contouring. Its sterile formulation ensures patient safety while delivering visible improvements.
Ingredients
Sodium Hyaluronate and Complexia 55
Main Active:
FatBlock ®: Pentapeptide-25, Hexapeptide-17, Acetyl Hexapeptide-39 and TCBC.
5 ways of action:
1.- Dissipating energy by uncoupling process UPC, Pentapeptide-25.
2.-Stimulation of microcirculation of blood and lymphatic drainage in the área Hexapeptide-17.
3.-Reducing adipocyte differentiation, Ac Hexapeptide-39 and TCBC.
Base components
- Sodium Hyaluronate
- Complexia 55 TM
4.-Diminishing lipid acumulation in adipocytes: Ac Hexapeptide-39 and
5.-Increasing fat burning, lipolysis, maduration of adipocytes, incorporation of lipids, TCBC
Indications
BelleVline peptide®is indicated for the treatment of
localized adipose tissue accumulation in the face and neck, with the objective of improving facial contour definition and the face–neck transition.
It is particularly suitable for areas where excess fat, tissue heaviness, or loss of contour clarity are present, including:
- Chin
- Double chin (submental area)
- Jawline
- Nasolabial region
Through the synergistic action of its peptide complex FatBlock™, BelleVline supports adipose tissue modulation, promotes progressive contour refinement, and contributes to a visible lifting and sculpting effect without inducing inflammation or tissue damage.
The formulation is specifically adapted to the sensitive tissues of the face, making it suitable for delicate facial zones where aggressive fat-reduction techniques are not indicated.
BelleVline Peptide® is intended for professional use only and must be administered under medical supervision.
Medical INFO
BelleVline peptide® is designed to improve facial contour definition through a multi-targeted modulation of adipose tissue metabolism. Its mechanism of action is based on complementary biological pathways involved in energy balance, lipid storage, adipocyte behavior, and tissue clearance, resulting in a progressive fat-reducing and contour-refining effect while respecting facial tissue physiology.
- Mitochondrial energy dissipation (UCP mediated uncoupling) Pentapeptide-25 shares structural similarity with uncoupling proteins (UCPs), a family of mitochondrial transporters involved in the regulation of energy expenditure. By promoting proton gradient dissipation at the mitochondrial membrane, Pentapeptide-25 reduces ATP synthesis and redirects energy toward heat production, leading to decreased lipogenesis and reduced lipid storage within adipocytes.
- Stimulation of lymphatic drainage and microcirculation Hexapeptide-17 acts on adipocyte cell receptors to enhance lymphatic drainage and local microcirculation. This mechanism facilitates the physiological elimination of lipids released during adipocyte lipolysis, preventing local accumulation and supporting tissue clearance.
- Inhibition of adipocyte differentiation Acetyl Hexapeptide-39 modulates signaling pathways involved in pre-adipocyte maturation, reducing adipocyte differentiation and limiting the formation of lipid-storing cells. This results in a decreased number of mature adipocytes capable of lipid accumulation.
- Reduction of intracellular lipid accumulation Acetyl Hexapeptide-39 has demonstrated a reduction of intracellular lipid accumulation in adipocytes of up to 67% compared with untreated differentiated cells, confirming its role in limiting fat storage at the cellular level.
- Stimulation of lipolysis and fat oxidation TCBC enhances lipolytic activity through hormonesensitive pathways, promoting triglyceride breakdown and fatty acid mobilization. Its fat-burning activity has shown efficacy comparable to that of caffeine, supporting increased lipid metabolism without inducing inflammatory stress.
BelleVline Peptide® is formulated for use on all skin types and is specifically adapted to the sensitive tissues of the face. Its non-aggressive profile allows effective contour refinement without irritation, pain, edema, or erythema, making it suitable for delicate facial zones.
Scientific Summary for Physicians
BelleVline Peptide® achieves facial contour refinement through a biomimetic, metabolism-based approach rather than adipocyte destruction. By simultaneously increasing energy dissipation, stimulating lipolysis, limiting adipocyte differentiation, reducing lipid storage, and supporting lymphatic clearance, BelleVline progressively reshapes localized facial fat deposits while preserving tissue integrity. This multi-pathway mechanism makes BelleVline particularly suitable for facial areas where precision, safety, and physiological compatibility are essential.
BelleVline peptide® is the regenerative bioactive solution for jawline definition and submental fat reduction. Contact Persebelle to integrate this into your clinic.
