Hyaluronidase is an effective product in the treatment of cellulite due to its fibrinolytic effect. It is also widely used in the correction of skin imperfections generated by hyaluronic acid.
Hyaluronidase modifies the permeability of epithelial and connective tissues promoting depolymerization of fibrous edema and facilitating local metabolic changes.
Depending on clinical criteria, prepare different units’ concentrations by using additional WFI.
The potency is typically prepared as 300 IU of hyaluronidase per ml, by reconstituting the vials with 5 ml WFI.
The application of Hyaluronidase 1500IU is to be supervised by a licensed physician in order to ensure safety measures.
Hyaluronidase.
Hyaluronidase is a lyophilized powder, in sterile and pyrogen free presentation. It increases the absorption of lipolytic substances when is combined with Cellu Peptide. Hyaluronidase is an endoglycosidase enzyme that modifies the permeability of connective tissue by hydrolysis of hyaluronic acid.
This globular enzyme can depolymerize hyaluronic acid in the dermis decreasing its viscosity, thus increasing the permeability of the tissue and reducing the edemas that commonly appear in cellulite.
Regarding the suppression of edemas generated by the abnormal accumulation of liquids, Hyaluronidase also has the capacity to digest chondroitin sulfate acid. Chondroitin is the major component of cartilage. Its negatively charged sulfate groups give it the property of retaining water and thus providing resistance.
Hyaluronidase acts not only by suppressing but also by preventing the formation of aggregates of this type of glycosaminoglycan in the connective tissue, thus preventing water retention and the formation of irregularities that become externalized on the surface of the skin.
Hyaluronidase promotes the penetration of other active substances through the skin and decreases the production of inflammatory mediators.
Hyaluronidase can also be used to counteract the undesirable effects of hyaluronic acid filler procedures used in cosmetics to minimize wrinkles or sagging of the face, or to augment other areas of the face.
