Two of the main ways of getting a real change in wrinkles appearance are the following:
- Acting over the face muscles blocking their contraction.
- Enhancing the synthesis of structural proteins in the Matrix of the Dermis.
FACEBOTOLIFT peptide® has got a fairly well balanced these two mechanisms. Liftimax LF5® has and optimal combination of biomolecules and actives that have showed in vitro impressive results by doing Botoxlike effect.
The mechanism of action, that blocks muscle contraction, resides on the Liftimax LF5®, which includes peptides that make a competitive inhibition of the SNAP-25 protein of the receptor of SNARE and blocks the formation of the SNARE complex in the motor neuron that is crucial for the liberation of Acetyl Choline.
As a consequence the muscle relaxes and is not able to do the contraction.
With time, this product gets reversion of Epidermal Junction from flat to wavy by enhancing the cohesion in the Matrix as it is found to up regulate the synthesis of fibrulin-5, fibrilin-1 and integrin.
FACEBOTOLIFT peptide®raises of the concentration of proteoglycans and structural proteins in the dermis by enhancing their synthesis and by inhibiting Metalloproteinase (MMP´s).