HAIR REVITALIZER peptide® provides the right substance for the synthesis of Prostaglandins that are key factors to Androgens signal regulation.
In the biology of the hair cycle there are synthesis of positive factors and negative factors, HAIR REVITALIZER peptide ®increase the synthesis of growth factors, like IGF-1, basic fibroblast factor (bFGF) and vascular endothelial growth factor (VEGF), maintaining the follicle in Anagen phase.
HAIR REVITALIZER peptide ® takes into account the key role of Androgens and WNT-beta catenin crosstalk. In some of the ingredients is remarkable the effectiveness in vitro sometimes better that Minoxidil and Finasteride. In some of the ingredients is remarkable the effectiveness in vitro sometimes better that Minoxidil and Finasteride.
HAIR REVITALIZER peptide® in a 6 months period activates the Anagen phase, an only leave 10-15% of the follicles in Telogen phase.
HAIR REVITALIZER peptide® stimulates hair growth, hair anchoring and improves blood circulation-nutrition consequently hair density.
HAIR REVITALIZER peptide® also presents the following actions:
1.- Inhibition of the action of BMP factors that blocks the WNT cytokine route.
2.- Regulation of the production of FGF-7, FGF-10, TGβ-2 and NOG, key growth factors for Stem Cell activation.
3.- Boost the presence of Adipocyte Precursor Cells APC in the adipose tissue increasing the production of Platelet Derived Growth Factor (PDGF), which is also a main factor for Stem Cell activation.
4.- Effective inhibition of 5-α-reductase in the cytoplasm by Biochanin A, down regulating DHT production, key factor in hair loss.
5.- Activation of the route of Bcl-2 proteins that activates mTOR hair growth genes and inhibits Bax and BH3, proteins that regulates apoptosis of the hair follicle cells.
6.- Increase the blood circulation by enhancing the Vascular Endothelial Growth Factor (VEGF) synthesis, main substance that promotes angiogenesis providing better nutrition to the dermal papilla of the hair follicle.
Hair Revitalizer peptide® is manufactured using aseptic filling technique that preserve all the actives. Also it is presented in sterile, preservative and pyrogen free conditions and can be used in several aesthetic techniques, roller, IPL, and other invasive or non-invasive medical aesthetic protocols.